I love Las Vegas!  Booking Las Vegas flights and then hitting the Strip is an exciting time for me!

The two most identified area of Las Vegas are the Strip and Downtown.
The strip is the most famous four mile road in the US. Most first time visitors
will spend most of their time on the Strip getting to know the way it works. It
has the most top hotels of any other road in the US.
The South strip is that portion of the Strip that has the MGM Grand, Mandalay
Bay, Luxor, and Monte Carlo. Don't overlook the New York New York with its
Manhattan skyline.
The Mid strip has Bellagio, Caesar's Palace, The Mirage and Treasure Island.
There is also the Venetian and the Wynn Hotel.
The North Strip has Circus Circus, the Stratosphere, and, until mid-2011, the
Sahara.
The East Strip has grown up around the Convention Center and Las Vegas is a
top convention center. The major hotel located here is the Las Vegas Hilton
and the Hard Rock Hotel is becoming a major hotel.
Between the Strip and Downtown, there is a bunch of wedding chapels,
pawnshops, and cheap motels. The area is called the Gateway District. It is
making a name for itself as an artist retreat. Other signs of life are sprouting up
such as coffee shops and small cafes.
Downtown is also known as Glitter Gulch. The neon lights become brighter
down here because of the narrow streets. This area is a lot more casual than
the Strip itself. The people are friendlier and it is not as snobby a place either.
With the start of the Fremont Street Experience, the downtown area has been
coming out of the ditches. Don't overlook this area, you may be surprised at
what you can find down here. It is a little distance from the strip, but it might
make the difference in your trip.